Hi,
Yes.
A typical add to cart/wishlist URL looks like that:
http://yourwebsite.com/component/hikashop/product/updatecart/add-1/quantity-XXX/cart_type-YYY/cid-ZZZ
where XXX is the quantity to add, YYY is either "cart" or "wishlist" and ZZZ is the product ID to add.
When the parameter "add" is set to 1, the quantity XXX will be added to the quantity of the product in the cart/wishlist.
When that parameter is set to 0, the quantity XXX will replace the quantity of the product in the cart.
So in short, you can use that URL:
http://yourwebsite.com/component/hikashop/product/updatecart/add-0/quantity-0/cart_type-wishlist/cid-ZZZ
and that will remove the product with the id ZZZ from the current wishlist.